GINAPS

Antimicrobial surface functionalization of PVC by a guanidine based antimicrobial polymer

Antimicrobial polyvinyl chloride (PVC) plastic was obtained by covalent bonding of poly hexamethylenediamine guanidine hydrochloride (PHMG), a guanidine based antimicrobial polymer. This was achieved by grafting mercaptopropyltrimethoxysilane onto …

Chitin hydrogel reinforced with TiO2 nanoparticles as an arsenic sorbent

In this work chitin hydrogels were reinforced with TiO2 nanoparticles acting as fillers. The mechanical and physicochemical characteristics of these hydrogels were studied by oscillatory rheology, infrared spectroscopy (FTIR), Scanning Electron …

Dermatan sulfate/chitosan polyelectrolyte complex with potential application in the treatment and diagnosis of vascular disease

Cardiovascular disease is the largest single cause of morbid-mortality in the world. However, there is still no pharmaceutical treatment that directly targets the blood vessel wall instead of just controlling the risk factors. Here, we produced …

Fluorescent responsive chlorophyllide-hydrogel for carbon dioxide detection

The chlorophyllide b derivatized polyallylamine (PAAChl) was synthesized. The resulting fluorescent polymer presented a high emission quantum yield, very stable in time. The polymer formed a hydrogel when treated with carbon dioxide that was …

Gem-Diol and Hemiacetal Forms in Formylpyridine and Vitamin-B6-Related Compounds: Solid-State NMR and Single-Crystal X-ray Diffraction Studies

The gem-diol moieties of organic compounds are rarely isolated or even studied in the solid state. Here, liquid- and solid-state NMR, together with single-crystal X-ray diffraction studies, were used to show different strategies to favor the gem-diol …

HmuS and HmuQ of Ensifer/Sinorhizobium meliloti degrade heme in vitro and participate in heme metabolism in vivo

Ensifer meliloti is a nitrogen-fixing symbiont of the alfalfa legume able to use heme as an iron source. The transport mechanism involved in heme acquisition in E. meliloti has been identified and characterized, but the fate of heme once inside the …

Innovative immobilization matrices

We present a brief survey of some of the recent work of Professor Luis E. Díaz, performed together with his students and collaborators at the University of Buenos Aires. Dr Luis E. Díaz has been involved in research on biochemical and pharmaceutical …

New Insights about the Selectivity in the Activation of Hydrogen Peroxide by Cobalt or Copper Hydrogel Heterogeneous Catalysts in the Generation of Reactive Oxygen Species

We report the performance of Co(II) and Cu(II) coordination complexes on H2O2 activation. The heterogeneous catalysts containing aliphatic amine, N-heterocycle, and/or carboxylic acid ligands in hydrogel materials coordinated with Co(II) or Cu(II) …

P120-catenin regulates early trafficking stages of the n-cadherin precursor complex

It is well established that binding of p120 catenin to the cytoplasmic domain of surface cadherin prevents cadherin endocytosis and degradation, contributing to cell-cell adhesion. In the present work we show that p120 catenin bound to the N-cadherin …

Surface chemistry of nanobiomaterials with antimicrobial activity

Biofilms are common in nature and are often associated with undesirable effects such as the deterioration of concrete, metal corrosion, fouling of oil and gas pipelines and ships hulls, dental plaques causing tooth decay, and microbial colonization …